• I would like to augment a fractional factorial design to a central composite design. The fractional factorial design consists of 2^(5-1) number of runs plus 3 centre points (n=19). Please suggest how do I go about augmenting the design to central composite design.</p> 2 years, 4 months ago

  • Thank you so much Mr. Robert.

    Yes, you are absolutely right. I need to be X% certain that my sample mean is within plus/minus some range (i.e., measurement error, 1-3SD). Please suggest the way I can calculate the sample size that covers 80% of the population with 95% confidence (Tolerance)? 2 years, 5 months ago

  • I have 100 batches of process data and I would like to estimate a sample size that is a representative of the entire population (covers at least 80% of the population). Please suggest different ways of calculating the sample size. 2 years, 5 months ago

  • I can convert the raw materials and supplements into continuous numbers by measuring one of their properties like Total Nitrogen, etc. In that case, what would be the option? 2 years, 7 months ago

  • The process has one raw material, one supplement and one catalyst: RM (A) + Supplement (B) + Catalyst (C) –> Yield.

    I have 15 raw materials available from 15 different suppliers: each raw material has a different composition (not known for Intellectual Property reasons) and are identified with a proprietary name.

    Same is the case with the…[Read more]

  • Hello,

    My objective is to develop a chemical process that has a raw material (A), a supplement (B), a catalyst (C) and the response variable is yield (R).

    I have 15 difference raw materials (A1, A2… A15), 4 catalysts (C1, C2, C3, C4) and 8 supplements (B1, B2…B8). I would like to design a DoE where I can find the combination of A, B and…[Read more]