Correct Test Method

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    Neil B

    I have a project in which a “device” will grow a biological sample based upon a sample from a patient. The issue is, the media in which the patient sample is going “end of life” and a new media will be used. How can I compare the old media and the new media using the same patient samples? Is it a GR&R, 2 Sample T test? It is a chemical application and I am just understanding the chemical processes involved.
    Thanks for any inputs,
    Neil (Not Lavoisier by any means) 



    It sounds like a hypothesis test of some sort is needed.
    The specific one you use will depend on the type of data you have for each thing that you are trying to compare:

    Is the data normally distributed
    Does the data have outliers

    There are flow charts available everywhere on the internet which guide you to the most appropriate test, for comparing means, or comparing variances of the two groups.
    The size of difference detectable between the two groups will be very much impacted by your sample size. Read up on it before starting anything.


    Jamilah Haron

    Since it is the same sample but just changing media, then you need to be clear of what you are measuring. Will the measurement affected by the interaction of sample in the media? Seems to be affected since you mentioned that it is chemical process. 
    Yes 2 sample t could be OK.

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