Assuming there is consistent process to judge when the cutter need to be changed , I would use chi-square goodness of fit test (from stat-tables).

Assuming that there is predefined consistent process to determine when the cutter need to change , I would use chi-square goodness of fit test (from stat-tables), stack before and after data in one column […]

Are you saying that you have multiple counts of acceptable cuts and that when you take an average of these multiple counts before the process you get an average of 2000 cuts and after the process change you get […]

I have already performed the DOE and determined that out of all of the factors mentioned above that cutter condition was the only significant factor. That is when we ran the 1FAT to see what the life of a cutter […]

@timfran87 – you’ve just described the multiple variables that you need to evaluate (and ultimately either control or render innocuous). A good DOE will include these different variables and show you main effects […]